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Research Ethics Journal Club
Back to Calendar 2007

 July 11, 2007

Topic: Conducting Unnecessary Research Studies
Presenter:
Wendy Bracken, Human Research Protection Program Coordinator
San Diego State University
Location: SDSU Foundation: Sky Park
Discussion:
In 2005, several papers highlighted a growing concern regarding clinical trials that were conducted far beyond the point at which sufficient data had been obtained. In one example, despite the number of relevant findings from earlier trials that babies sleeping on their backs were less likely to die of SIDS, superfluous studies continued to be conducted. Bad research practices such as this can lead to a myriad of troubling outcomes ­ from wasted grant money to unnecessary deaths. This discussion will focus on what can and should be done to revise the practice of conducting unnecessary research studies.
Readings:
  • "Superfluous Medical Studies Called Into Question". David Brown. Washington Post, Jan 2, 2006; Page A06

  • "Putting clinical trials in context". Charles Young; Richard Horton. The Lancet, Jul 9-July 15, 2005; 366.

  • "Academia's failure to support systematic reviews". Iain Chalmers. The Lancet, Feb 5 - Feb 11, 2005; 365.

  • “Discussion Sections in Reports of Controlled Trials Published in General Medical Journals.” Mike Clarke, Phil Alderson, Iain Chalmers. JAMA, 2002;287:2799-2801

Note: For those Journal Club members at UCSD, some readings are available through electronic reserves in the UCSD Biomedical Library. Go to http://reserves.ucsd.edu, click "Electronic Reserves & Reserves Pages", select the "Pages by Instructor" tab, select instructor "Kalichman", and click "View". On the Course Reserves page, click "SOM300", read and accept the copyright statement, open the Journal Club folder, and find the files in this month's file. For those not at UCSD, please e-mail us at ethics@ucsd.edu and we will send you a PDF attachment.